Our knowledge of God really matters a lot. There's a limit to which man's ability can reach, but not with God. The bible says He knows the end of a thing from the beginning. Man's reasoning cannot be compared with that of God. No matter how smart we think we are—maybe because of the level of knowledge we have or qualifications we have acquired—where our wisdom ends is where God's wisdom begins.
Even the devil in all His craftiness is still very much far behind. We see something of this sort in the bible concerning our Lord Jesus Christ. Even before His birth, the devil tried every means to ensure that He didn't come into this world because he knew Christ's birth was the remedy to mankind. But all the schemes came to no avail. He thought he could succeed by bringing about the death of Jesus.
But that's where he made the mistake, because it was death that later on brought the salvation of man. The bible recorded that is the prince of this world had known that through Jesus' death man would be saved he wouldn't have let them crucify Jesus, because crucifixion was the only way salvation could have been brought to us and not by any other form of death.
What this is trying to say in essence is that God is always far ahead of us in reasonings and otherwise. The wisdom of this world can help us up to an extent, but through wisdom comes from God.