Yes, you should be able to, as well as picking which countries you do or don't ship to.
Below is the Account Settings screen. It's the UK version (my secondary personal account, not my main business one, which looks very different !), but hopefully the Irish one isn't too different ! I've ringed the interesting bits in red....
This is the Shipping settings screen accessed from the previous one;
You may not have Click & Collect in Ireland, but you may well have Global Shipping. It's an easy way to do international, but is expensive for buyers, so only worth doing if you're not that interested in international sales.
The "Exclude Postal Locations" setting takes you to a screen where you can select country by country, or for whole continents, where you don't ship to.
"Postage Rate Tables" is where you can set postage rates up country by country, although it's a pig to work out the fine detail.
But I spotted that they'd opened up Business Policies to non-business sellers. Although it's slightly less flexible in terms of individual country settings, once set up it makes the actual listing process a total doddle !