Sleep deprivation, both complete and partial, may harm a person in different ways- threat to safety, poor work performance, and some serious health issues, including a heart attack!!

In fact, a number of studies of hand-eye coordination and reaction time have shown that such sleep deprivation can be as debilitating as intoxication. In one study, 24 hours of wakefulness caused as much impairment as a blood alcohol content of 0.10%.

More details in this Harvard Health article

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